| 초록 |
Conductive and injectable hydrogels have attracted in the healthcare field such as tissue repair and flexible electronics due to their electrical responsibility and facile extrusion for 3D printing. However, there are still hurdles to achieve their high conductivity and controllable mechanical properties without post-printing process. Herein, we developed conductive hydrogels through homocoupling of phenylboronic acids catalyzed by metal ions. For that, polymeric backbone, phenylboronic acid-tethered hyaluronic acid, was crosslinked by gold ions under mild basic conditions. Depending on the stoichiometric ratio of base and gold ions, the rheological properties were easily desirable, resulting in reversible conductivity and injectability for 3D printing. By filling the hydrogels to muscle defect in vivo, the electrophysiological signals by muscle contraction could be recovered. The conductive, and injectable hydrogels can be applied for engineering electroactive tissue support material. |
