| 학회 |
한국공업화학회 |
| 학술대회 |
2010년 봄 (05/13 ~ 05/14, BEXCO(부산)) |
| 권호 |
14권 1호 |
| 발표분야 |
고분자 |
| 제목 |
Artificial skin substitutes for development of alternative tests to animal experiments |
| 초록 |
Currently available skin substitutes often suffer from a range of problems that include poor integration, scarring at the graft margins and a complete lack of differentiated structures. This study focused on the development of polymeric artificial skin with good biocompatibility and physical property by using radiation technique. We designed the artificial skin model composed of biocompatible natural polymer and synthetic polymer with high mechanical property for alternative tests to animal experiments. We synthesized hyaluronic acid and chodroitin sulfate derivatives with polymerizable residues with precise control over the substitution degree. The glycosaminoglycan-based hydrogels were prepared and their physicochemical propertieswere investigated to evaluate the feasibility for artificial skin substitutes. |
| 저자 |
이수지1, 임윤묵2, 권희정2, 노영창2, 김소연1
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| 소속 |
1충남대, 2한국원자력(연) |
| 키워드 |
hydrogel; tissue engineering; skin substitutes
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| E-Mail |
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