화학공학소재연구정보센터
학회 한국재료학회
학술대회 2009년 가을 (11/05 ~ 11/06, 포항공과대학교)
권호 15권 2호
발표분야 D. Health and Biological Materials(생체 및 의용재료)
제목 Fabrication and characterization of PCL/TCP-coated PHBV composite multilayer as a bone plate
초록 In this work, Poly(ε-Caprolactone)(PCL) and poly(3-hydroxybutyrate-co-3-hydroxyvalerate)(PHBV) mats were fabricated using electrospinning process. The electrospinning process is a simple and efficient method to fabricate the nanofibrous mats. PCL and PHBV is a kind of biodegradable polymer but their mechanical properties aren’t good. For improving mechanical properties, PHBV mats were coated by TCP. Using PCL mats and TCP-coated PHBV composite mats, a bio-resorbable bone plate were made by pressing. Detailed micro-structural characterization was done by SEM techniques. Tensile strength and bending strength were also evaluated for mechanical properties. The cytotoxicity evaluation of PCL/TCP-coated PHBV composite multilayer was done by MTT assay. The evidence obtained in this work implies the potential for use as a biodegradable bone plate.
저자 Yang Hee Kim1, Ho Yeon Song2, Byong Taek Lee3
소속 1Department of Biomedical Engineering and Materials, 2School of Medicine, 3Soonchunhyang Univ.
키워드 PCL; PHBV; TCP; electrospinning; bone plate
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