| 초록 |
Magnetite nanoparticles are suitable for receptor targeting because of their colloidal stability, biocompatibility, biodegradability, and nontoxicity for the body. Receptor-targeting has been used to deliver contrast-producing superparamagnetic iron oxide nanoparticle to receptor-expressing tumors for magnetic resonance imaging. In this study, polysaccharide-immobilized nanoparticles (SNP) were prepared by coprecipitation method using ferric chloride, ferrous chloride and dextran. Oligopepide (9amino acid sequences) and fluorescence isothiocyanate (FITC) were then introduced to the surface of nanoparticles to recognize tumor cells and to get fluorescence image, respectively. |
