| 학회 |
한국고분자학회 |
| 학술대회 |
2015년 봄 (04/08 ~ 04/10, 대전컨벤션센터) |
| 권호 |
40권 1호 |
| 발표분야 |
의료용 고분자 부문위원회 II |
| 제목 |
Antibacterial activity and cyto-compatibility of PLGA/CuO hybrid nanofiber scaffolds prepared by electrospining |
| 초록 |
The PLGA/CuO hybrid nanofiber scaffolds were prepared via electrospinning technique. The presence of CuO in the PLGA scaffolds was confirmed by transmission electron microscope (TEM) and x-ray photoelectron spectroscopy (XPS). The scaffolds were subjected to various antibacterial and biocompatibility tests. The results not only showed excellent adhesion, proliferation and viability (live/dead staining) for fibroblastic cells but also revealed that PLGA/CuO hybrid nanofiber scaffolds inhibited both gram positive and gram negative bacterial growth. The mechanism of the antibacterial activity was concluded to be based on the CuO nanoparticles and Cu++ ion release. It is therefore, evaluated that PLGA/CuO hybrid nanofiber scaffolds can be a useful candidate for wound dressing and an alternate implanting material after post surgical operation. |
| 저자 |
하이더 아드난, 강인규
|
| 소속 |
경북대 |
| 키워드 |
PLGA; CuO; electrospining; biocompatibility; antibacterial activity
|
| E-Mail |
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