| 초록 |
Anisotropic dispersive particles in micro- to nanometer scale have been extensively explored for their unique functionality in a wide range of areas. In particular, polymeric one-dimensional nanostructures including nanorods, nanotubes, and nanofibers have great potential for building blocks for biomedical devices, drug delivery systems and regenerative medicine with the advantages of having large surface area, achieving ordered array, and resembling with extracellular microenvironment. In recent years, electrospinning has gained much attention for fabricating polymeric ultrafine fibers down to 10 nm with feasibility of spinning a wide range of synthetic or natural polymers and versatility of making complex nanostructures such as hollow or multichannel tubes and nanorod-on-nanofiber hierarchical structure. Here we developed a facile and cost effective top-down approach for fabricating rod-like materials composing of biodegradable and biocompatible polymer from electrospun nanofibers. |
