| 학회 |
한국고분자학회 |
| 학술대회 |
2004년 봄 (04/09 ~ 04/10, 고려대학교) |
| 권호 |
29권 1호, p.196 |
| 발표분야 |
의료용 고분자 부문위원회 |
| 제목 |
A novel approach to bioactive nanobiomaterials based on functionalized mesoporous silica materials |
| 초록 |
The highly ordered mesoporous silica materials have the controllable pore dimension and large specific surface area. Their highly ordered pore structure make themselves a very suitable for the encapsulation or immobilization of biomolecules by using various functional groups on the inner or outer surface. In addition, the develpoment of sol-gel methods under the ambient condition have been interested as a new way to encapsulate biomolecules within porous materials as well as maintain their biological activities. In this study, a sulfonated and a heparinized mesoporous silica prepared by sol-gel method were investigated for medical device applications. A sulfonated surface was prepared by the oxidation. The heparinized surfaces were prepared by physicochemical immobilization of heparin to functionalized mesoporous silica. The surface properties were characterized and the blood compatibility is now under evaluation. |
| 저자 |
배진우, 김동찬, 박형달, 김지만, 박기동
|
| 소속 |
아주대 |
| 키워드 |
mesoporous; nanobiomaterials; heparin
|
| E-Mail |
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