화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2005년 봄 (05/13 ~ 05/14, 충남대학교)
권호 9권 1호
발표분야 생물공학
제목 Optimization of culture condition for Haematococcus pluvilalis mutants using central composite design (CCD)
초록 Recently, algal biotechnology has received increasing interests and is becoming one of the frontiers of the biotechnology. Especially a green alga H. pluvialis has received increasing interest as one of the best producers of astaxanthin (3,3'-dihydroxy-β,β-carotene-4,4'-dixone) due to its antioxidant activity, approximately ten times greater than other carotenoids.
To enhance astaxanthin production by Haematococcus pluvialis, three types of mutant stains, obtained from UV irradiation and colchicine treatment, were selected among 50,000 colonies appeared after mutations. The selected mutant cells were named as U15_5, DS and M3 respectively, and they showed either 20-30% faster cell growth or 30-70% higher astaxanthin accumulation compared to those from wild type strains.
저자 정성은, 이호상, 이철균
소속 인하대
키워드 Haematococcus pluvialis; CCD; central composite design
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