| 학회 |
한국화학공학회 |
| 학술대회 |
2013년 봄 (04/24 ~ 04/26, 광주 김대중컨벤션센터) |
| 권호 |
19권 1호, p.698 |
| 발표분야 |
재료 |
| 제목 |
Aptamer immobilized nanosensor for label free and real time detection of metal ions and cancer marker |
| 초록 |
Nanowire sensors are emerging as one of the most outstanding platforms for specific identification of biomolecules in the life sciences. To date, there have been many reports for chemical and biological nanosensors using one dimensional nanostructure and various functionalization schemes. For the purpose of commecialization, it has been recognized that control of the solution Debye length is critical for highly sensitive detection of biomolecules. To address these issues, we tried to demonstrate that aptamers enable sensitive detection possibles because they are smaller in size than the Debye length. For this work, we have fabricated label free nanosensors based on aptamer-modified ZnO/PAC(polymer-like amorphous carbon) nanowire field effect transistors. we investigated the real-time, label free for detection of Cu metal ion and AFP antigen in solutions. Finally, the electrical signals of nanosensors according specific bindings on nanowire field effect transistor were discused in terms of ions screening effects, as compared to the conventional approach |
| 저자 |
김진태, 구아영, 송정근, 서지혜, 육영근, 임연호
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| 소속 |
전북대 |
| 키워드 |
biosensor |
| E-Mail |
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| 원문파일 |
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