| 학회 |
한국재료학회 |
| 학술대회 |
2009년 가을 (11/05 ~ 11/06, 포항공과대학교) |
| 권호 |
15권 2호 |
| 발표분야 |
D. Health and Biological Materials(생체 및 의용재료) |
| 제목 |
Aerosol Deposition and Its Potential Use for Bioactive Ceramic Coatings |
| 초록 |
Aerosol Deposition (AD) is a novel way to fabricate bioactive ceramic coatings in biomedical implants and prostheses applications. In the present work, silicon-substituted hydroxyapatite (HA) coatings on commercially pure titanium were prepared by aerosol deposition using Si-HA powders. The incorporation of silicon in the HA lattice is known to improve the bioactivity of the HA, making silicon-substitute HA an attractive alternative to pure HA in biomedical applications. Si-HA powders with the chemical formula Ca10(PO4)6-x(SiO4)x(OH)2-x, having silicon contents up to x=0.5 (1.4 wt%), were synthesized by solid-state reaction of Ca2P2O7, CaCO3, and SiO2. The Si-HA powders were characterized by X-ray diffraction (XRD), X-ray fluorescence spectrometry (XRF), and Fourier transform infrared spectroscopy (FT-IR). The corresponding coatings were also analyzed by XRD, scanning electron microscopy (SEM), and electron probe microanalyzer (EPMA). The results revealed that a single-phase Si-HA was obtained without any secondary phases such as α- or β-tricalcium phosphate (TCP) for both the powders and the coatings. The Si-HA coating was about 5 μm thick, had a dense microstructure with no cracks or pores. In addition, the proliferation and alkaline phosphatase (ALP) activity of MC3T3-E1 preosteoblast cells grown on the Si-HA coatings were significantly higher than those on the bare Ti and pure HA coating. These results revealed the stimulatory effects induced by silicon substitution on the cellular response to the HA coating. |
| 저자 |
Byung-Dong Hahn1, Dong-Soo Park2, Jeong-Min Lee1, Jong-Jin Choi2, Jungho Ryu1, Woon-Ha Yoon2, Byoung-Kuk Lee1, Joon-Hwan Choi2, Hyoun-Ee Kim1
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| 소속 |
1Functional Ceramics Research Group, 2Korea Institute of Materials Science |
| 키워드 |
Aerosol Deposition; Hydroxyapatite; Silicon; Coating
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| E-Mail |
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