| 학회 |
한국공업화학회 |
| 학술대회 |
2010년 봄 (05/13 ~ 05/14, BEXCO(부산)) |
| 권호 |
14권 1호 |
| 발표분야 |
콜로이드계면화학 |
| 제목 |
Size and Morphology Control of Biodegradable Stimuli-sensitive Aggregates from Supramolecular Graft Copolymers |
| 초록 |
Supramolecular graft copolymers (SGPs) composed of PLL and PLGA was made in DMSO. The carboxylic end groups of PLGA were grafted into primary ε-amine groups in PLL with different degree of substitution through ionic interaction. Water addition induced self-assembly of PLL/PLGA SPGs into spherical micelles at critical water content (CWC). Further increase of water content caused morphology transition from spherical micelles to vesicles and returned to spherical micelles following addition of DMSO. Aggregates showed pH and salt sensitivity. Aggregates dissociated around the pKa value of the primary ε-amine group in PLL and 0.15 M NaCl concentration. |
| 저자 |
조영민, 박찬우, 정보경, 양희만, 김종득
|
| 소속 |
KAIST |
| 키워드 |
Supramolecular Graft Copolymer; Size; Morphology; Stimuli-sensitivity
|
| E-Mail |
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