화학공학소재연구정보센터
학회 한국화학공학회
학술대회 2004년 봄 (04/23 ~ 04/24, 공주대학교)
권호 10권 1호, p.384
발표분야 생물화공
제목 Medium Development for Ansamitocin P-3 production with Actinosynnema pretiosum ATCC 31565 using Statistical Approach
초록 Statistical techniques were adopted for medium development of ansamitocin P-3 production using Actinosynnema petisoum ATCC 31565. Plackett-Burman design was used to screen out the nutritional factors which effects on antibiotic production. Out of 11 factors studied by Plackett-Burman design, six influenced the antibiotic production. Further, Central composite Design (CCD) and Response surface methodology (RSM) were used to optimize the significant factors (sucrose, dextrin, yeast extract and poly peptone) and response surface plots were generated. Using these response surface plots, optimized values of the factors were determined for higher ansamitocin P-3 production.
저자 Srinivasulu Bandi1, 김윤정2, 사순옥1, 장용근2
소속 1Department of Chemical and Biomolecular Engineering, 2Korea Advanced Institute of Science and Technology
키워드 Ansamitocin; Plackett-Burman design; RSM
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