| 초록 |
There are many reports on preparation of hollow polymeric spheres that can be classified largely as chemical methods and physical methods. Emulsion polymerization, suspension polymerization, interfacial polymerization, and radical polymerization carried out in the presence of templates are typical examples for chemical methods where in situ polymerization is involved. Other chemical methods include removal of templates coated with polymers by chemical means. In physical methods, no chemical reaction is involved throughout the process. Deposition of polymer molecules on physically removable templates and incomplete phase inversion method are the most representative physical methods to prepare hollow polymer spheres. In this study, polymer solutions were dispersed in aqueous media to obtain emulsions and phase separation to solvent-rich phase and polymer-rich phase was induced inside the oil drops by allowing the solvent to evaporate at room temperature. This method can be applied to other polymers such as PLGA and bacterial polyesters. Coating with other inorganic layer gave spheres with different morphology and allowed us to entrap lyophilic molecules within the spherical structures that was demonstrated using soybean oil in this study. |
