| 학회 |
한국화학공학회 |
| 학술대회 |
2005년 봄 (04/22 ~ 04/23, 여수대학교) |
| 권호 |
11권 1호, p.675 |
| 발표분야 |
이온성액체(Ionic Liquid)의 열물성과 이용기술 |
| 제목 |
Application of Ionic Liquids in Biotechnology |
| 초록 |
Ionic liquids are compounds that composed only of ions and are liquid at room temperature. Thus, it is normally named room temperature ionic liquid (RTIL). RTILs are environmentally benign, non toxic and have excellent physical and chemical properties as a substitute of conventional organic solvents. However, few studies have been conducted on biotechnology. In this study, the application of RTILs to the enzyme reaction and extractive fermentation of biomaterials was investigated as a substitute of organic solvents. For enzyme reaction, lipase is stable at temperature as high as 60℃. The acylation of sucrose was accomplished at 50℃. The optimum conditions for the acylation of sucrose, such as molar ratio of substrates, lipase, water, and ionic liquid, were determined. The relative toxicity of the RTILs on the growth of E. coli was tested. The inhibition of cell growth in the presence of various ionic liquids was measured using EC50. Effective concentrations of toxicity (EC50) in these tested systems were similar with conventional solvents. The viability of E. coli was affected by the polarity and ionic properties of ionic liquids. The resistance of the microorganisms against ionic liquids was different with the cations and anions composing ionic liquids. |
| 저자 |
이상목, 장우진, 문윤희, 최아롬, 김영준, 구윤모
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| 소속 |
인하대 |
| 키워드 |
ionic liquids; toxicity; acylation; E. coli; sucrose laurate
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| E-Mail |
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| VOD |
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| 원문파일 |
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