| 학회 | 한국화학공학회 |
| 학술대회 | 2006년 봄 (04/20 ~ 04/21, 대구 인터불고 호텔) |
| 권호 | 12권 1호, p.421 |
| 발표분야 | 생물화공 |
| 제목 | Effects of Sodium Bicarbonate on Cell Growth and Succinic Acid Production of Mannheimia succiniciproducens MBEL55E in Anaerobic Batch Fermentation |
| 초록 | Mannheimia succiniciproducens MBEL55E isolated from Korean bovine rumen produces a large amount of succinic acid under anaerobic conditions. Anaerobic batch fermentations were performed at various concentrations of sodium bicarbonate ranging from 2.5 to 20 g/L in a 5-L reactor. Sodium bicarbonate is normally served as a buffering agent and its solubilized carbon dioxide form in a liquid medium could be used at CO2-fixation reactions. CO2-fixation reactions in M. succiniciproducens occur for the conversion of phosphoenolpyruvate and pyruvate to oxaloacetate and malate, respectively. The supplementation of sodium carbonate enhanced the production of succinic acid and this work shed light on the development of a process optimization for microbial succinic acid production. [This work was supported by the Genome-based Integrated Bioprocess Project of the Ministry of Science and Technology. Further supports by the LG Chem Chair Professorship, IBM SUR program, Brain Korea 21 project, and by the KOSEF through the Center for Ultramicrochemical Process Systems are appreciated] |
| 저자 | 송효학, 이상엽 |
| 소속 | 한국과학기술원 |
| 키워드 | Mannheimia succiniciproducens; succinic acid; sodium bicarbonate; CO2-fixation |
| 원문파일 | 초록 보기 |
