| 초록 |
Recently, more studies have been conducted in chemical and biological applications using microfluidic or nanofluidic devices. However, it is still challenging to control of the surface properties of these devices on demand. In this paper, we utilized layer-by-layer deposition method to modify the surface of the micro-channel of the device in order to control cellular interactions inside of the channel. We have been studied cellular interactions on various polyelectrolyte multilayer films on open surfaces. Multilayer films comprised of weak polyelectrolytes exhibit different surface properties as they were assembled at different pH conditions. Therefore, cellular interactions including adhesion can be shown differently by depending on the PEM surfaces. Polyelectrolytes including biodegradable polymer such as poly(hyalulonic acid) (HA) was investigated for their surface-cell interaction using epithelial cells and immune cells. |
