화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2006년 봄 (04/06 ~ 04/07, 일산킨텍스)
권호 31권 1호
발표분야 의료용 고분자 부문위원회
제목 Engineering Biomaterials to Modulate Cell/Tissue Function
초록 Cells are embedded within complex microenvironment consisting of extracellular matrix (ECM), growth factors, and cytokines. Cell adhesion to ECM triggers a cascade of intercellular signaling events that lead to changes in important cellular behaviors. The current strategy for developing engineered tissue involves combining cells with scaffolds that provide the initial framework for cells to assemble into tissue. Therefore, the ability to modulate cellular interactions with their microenvironment is critical to regenerate biologically functional tissue. Conventional tools in material engineering and cell/molecular biology are now being adopted to creating novel structure that provides spatially and structurally defined biological signals to cells and directs desirable cellular responses. This presentation will highlight some of recent advances in understanding of how miroenvironmental cues, presented from engineered biomaterials, can affect cellular phenotype and function.
저자 신흥수1, Andres J. Garcia2
소속 1한양대, 2Georgia Institute of Technology
키워드 cell-biomaterial interaction; tissue engineering
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