| 초록 |
It is well known that varying temperature can alter the hydrophobic/hydrophilic property of PEO-PPO-PEO block copolymer, commercially available as Poloxamers or Pluronics, in aqueous solutions. In this study, poly(2-hydroxyethyl methacrylate) (PHEMA) based hydrogels containing varying amount of Pluronic F127, end-capped with methacrylate reactive groups, were synthesized either by thermal- or photo-polymerization technique. The effects of Pluronic F127 macromer on the properties of those copolymer hydrogels were investigated in terms of swelling and transmittance changes depending on the composition and environmental temperature. Those Pluronic-containing PHEMA copolymer hydrogels present a potential application in current controlled drug delivery and tissue engineering. |
