화학공학소재연구정보센터
학회 한국화학공학회
학술대회 2019년 봄 (04/24 ~ 04/26, 제주국제컨벤션센터)
권호 25권 1호, p.363
발표분야 생물화공(Biochemical Engineering)
제목 Production of 5-Aminovaleric acid from metabolically engineered Corynebacterium glutamicum
초록 5-Aminovaleric acid (5AVA) is an important five-carbon platform chemical especially for synthesis of polymers and other industrially valuable chemicals. Employment of davB davA gene has been successful for enzymatic conversion of L-lysine to 5AVA. Corynebacterium glutamicum, an efficient L-lysine producing microorganism, is a highly promising platform to develop of direct fermentative production of 5AVA using L-lysine as a precursor for 5AVA. In this report, metabolic engineering was done in C. glutamicum to enhance the fermentative production of 5AVA from glucose. This work was supported by the Technology Development Program to Solve Climate Changes on Systems Metabolic Engineering for Biorefineries from the Ministry of Science and ICT through the National Research Foundation of Korea [NRF-2012M1A2A2026556 and NRF-2012M1A2A2026557]
저자 한태희, 신재호, 조재성, 이상엽
소속 한국과학기술원
키워드 생물화학공학
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