| 초록 |
Cadaverine can be used a monomer for polyamide with dicarboxylate such as adipic acid. Recent research environment has driven the sustainability as a major goal of chemical production in next generation. In such a viewpoint, production of polymers using cadaverine, which can be produced from L-lysine, is highly preferred. In this work, we studied the screening of lysine decarboxylase. L-lysine was used as limiting C-source and N-source in minimal culture. As a result, we have screened Achromobacter sp. which shows higher activity in the α-decarboxylation reaction of L-lysine. In whole cell reaction in pH 5.8, A. sp. showed 4.5×10-3 μmol/min mg(dcw) while Escherichia coli K-12 showed 2.6×10-3μmol/min mg(dcw). |
