화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2015년 가을 (11/04 ~ 11/06, 제주국제컨벤션센터(ICCJEJU))
권호 19권 2호
발표분야 콜로이드계면화학_포스터
제목 Stiffness-modulating bioactive hydrogel with micro-channeled piezoelectric membrane  
초록 This study demonstrates that a new method to align and control spatial organization of bioactive hydrogel into micro-channels of a poly(vinylidene fluoride) membrane and guide growth direction and spacing of living cells. This integrated bioactive hydrogel system was prepared by fabricating a micro-channeled PVDF membranes and subsequently filling micro-channels with a hydrogel of biologically active collagen. The micro-channeled PVDF was fabricated by inducing the directional growth of cylindrical solvent crystals at a controlled freezing speed and removing them by lyophilization.  Finally, the aligned micro-channels were filled with a collagen hydrogel in a vacuum for guiding and leading the myoblasts into the patterned myotubes.        
저자 정재현1, 이민경2, 김희진1, 신성규1, 조성우1
소속 1숭실대, 2삼성전자
키워드 Stiffness; Hydrogel; Microchanneled; Networking
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