| 학회 | 한국고분자학회 |
| 학술대회 | 2003년 가을 (10/10 ~ 10/11, 부경대학교) |
| 권호 | 28권 2호, p.178 |
| 발표분야 | 의료용 고분자 부문위원회 |
| 제목 | Evaluation of cell proliferation and adhesion on PE film surface with different wattability. |
| 초록 | When cells are suspended in such a medium and are placed on a synthetic substrate it is not the cell that immediately interact with the surface but the serum proteins. It has been recognized that adhesion and proliferation of cells on low density poly ethylene (LDPE) films depend on the surface properties. Plasma treatment of LDPE films was developed to increase surfaces wettability and to improve adhesion and proliferation of BMSCs. The modified surface were characterized by the measurement of the static contact angle, electron spectroscopy for chemical analysis (ESCA). The adhesion and proliferation of cells on LDPE films were characterized by MTT assay, scanning electron microscopy (SEM), and reverse transcription-polymerase chain reaction (RT-PCR). The water contact angle of the film surface was gradually decreased with increase of plasma treatment time. By analyzing the pattern of expression exhibited by several growth-associated genes (e.g., c-fos, c-myc, p53) in BMSCs following water contact angle. Acknowledgement : This work was supported by MOWH (IMT-2000, 01-PJ11-PG9-01NT00-0011). |
| 저자 | 김은정1, 박기숙1, 이상진2, 김문석2, 조선행2, 이해방2, 강길선1 |
| 소속 | 1전북대, 2한국화학(연) |
| 키워드 | PE film; plasma; BMSCs; contact angle |
