화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2020년 가을 (10/28 ~ 10/30, 광주 김대중컨벤션센터(Kimdaejung Convention Center))
권호 24권 1호
발표분야 포스터-생체재료
제목 Antioxidative effect of PGC-1α-derived peptide material conjugated with gallic acid
초록 In the past few centuries, aging has become a part of global interest. Skin is one of the areas where aging occurs quickly and is affected by environmental exposure and genetic processes. The use of suitable cosmetic anti-aging substances, which use suitable biomolecules, can help protect damaged skin tissue. In particular, the antioxidant and anti-inflammatory effects of functional materials are important factors in the management of skin physicochemical and biological oxidative stress. This study investigated the important function of Galloyl-peptide (derived from PGC-1α) to confirm that it meets the requirements of cosmetic anti-aging biomolecules. The biocompatibility of Galloyl-peptide was confirmed by CCK-8 analysis, and the antioxidant effect was confirmed by DPPH. This new approach indicates that Galloyl-peptide is a potentially cosmetic anti-aging biomaterial for the prevention of oxidative stress.
저자 이후민1, 김형식2, 황목찬3, 김준영2, 김광자3, 박치후2, 허윤석1
소속 1인하대, 2옙바이오(주), 3㈜디마인화장품
키워드 anti-oxidant; peptide; gallic acid
E-Mail