초록 |
we synthesized PEG–derivatized phosphine oxide (PO-PEG) ligands from the simple reaction of POCl3, bis(dichlorophosphino)ethane and PEG, respectively. The PO-PEG ligands can be readily endowed with surface functional groups for the conjugation with biomarkers and bio-active materials. The overall synthetic process is very simple and inexpensive, and can be readily applicable for the large-scale production of water-dispersible and biocompatible oxide nanocrystals for various biomedical applications. |