| 학회 |
한국고분자학회 |
| 학술대회 |
2002년 가을 (10/11 ~ 10/12, 군산대학교) |
| 권호 |
27권 2호, p.177 |
| 발표분야 |
의료용 고분자 부문위원회 |
| 제목 |
A Novel Electrospun Nanofibrous Scaffold for Tissue Engineering |
| 초록 |
For many years, there are several approaches in three dimensional scaffolds design for tissue engineering. Biodegradable natural and synthetic polymers have been processed into scaffold materials. Among them, collagen, natural polymer, is widely used for three dimensional tissue regeneration. In many organ tissues, extracellular matrix (ECM) is consisted of two macromolecules, proteoglycans and collagens, that together form a composite-like structure. The collagen fibrous structure is composed by three-dimensional fiber networks of nanometer-scale (50 - 500 nm) multi-fibrils. This nano-scale fibrillar structure provide a better environment for cell attachment and function. In this study, we prepared a novel nonwoven nano-scale fiber-based scaffold by an electrospinning process for having a morphologic similarity to the ECM. The obtained nanofibrous scaffold was physicochemically modified with plasma glow discharge treatment for improving cell adhesion. The properties of the scaffold, including porosity and mechanical properties, were characterized and cell compatibilities onto surface modified and control nanofibrous scaffolds were also investigated. |
| 저자 |
주영민1, 안광덕2, 김정래*3, 조성무*, 천석원**, 한동근
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| 소속 |
1한국과학기술(연), 2*고분자하이브리드연구센터, 3**(주) 삼신크리에이션 나노섬유연구센터 |
| 키워드 |
조직공학(tissue engineering); 나노섬유(nanofiber)
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| E-Mail |
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