| 학회 |
한국화학공학회 |
| 학술대회 |
2006년 봄 (04/20 ~ 04/21, 대구 인터불고 호텔) |
| 권호 |
12권 1호, p.62 |
| 발표분야 |
공업화학 |
| 제목 |
The High Yields Purification of Human DNA with Functionalized Self-Assembled Mesoporous Silicas |
| 초록 |
This work describes the innovative development of high throughput human DNA purification process using the molecular self-assembled mesoporous silicas. The mesoporous silicas were prepared by sol-gel method and the formation of molecular self-assembled monolayers on the mesoporous silica with functional groups was chemically demonstrated. The surface modification of functional groups was performed with amino-functionallized organosilanes. The characterization of the prepared amino-functionalized self-assembled mesoporous silicas was obtained by BET, FT-IR(ATR-method), and TG. The solid-state 29Si, 13C-NMR were used to determine the chemical information of the aminofunctionalized mesoporous silicas surroundings on the Si, and C, respectively. The DNA binding result shows the optimum values as a function of functional groups and their efficiencies were also calculated. |
| 저자 |
조민애1, 박무언1, 장정호1, 김경자1, 김우년2
|
| 소속 |
1한국요업(세라믹)기술원, 2고려대 |
| 키워드 |
mesoporous silicas |
| E-Mail |
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| 원문파일 |
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