| 학회 |
한국공업화학회 |
| 학술대회 |
2009년 가을 (10/15 ~ 10/16, 서울산업대학교 내 서울테크노파크) |
| 권호 |
13권 2호 |
| 발표분야 |
약물 전달시스템의 최근 개발 동향 심포지움 |
| 제목 |
Enhancement of Osteoblastic differentiation on mesenchymal stem cells by chitosan |
| 초록 |
Chitosan is produced commercially by deacetylation of chitin, whiche is the structural element in the exoskeleton of crustaceans (crabs, shrimp, etc.). Chitosan enhances the transport of polar drugs across epithelial surfaces, and is biocompatible and biodegradable. Chitosans are available for biomedical applications. In this study, we evaluated the effect of water-soluble chitosan on the osteogenic differentiation of mesenchymal stem cells (D1 cells). We suggest that water-soluble chitosan enhances osteoblast differentiation through the induction of calcium deposit and the enhancement of surface molecules, such as, CD44 and CD51. |
| 저자 |
김형근1, 윤택림2, 김지현2, 장미경3, 나재운3
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| 소속 |
1전남대, 2화순전남대, 3순천대 |
| 키워드 |
calcium; CD44; CD51; chitosan; mesenchymal stem cells
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| E-Mail |
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