| 초록 |
Oxidised cellulose (OC) and oxidised regenerated cellulose (ORC) containing carboxyl groups represent an important class of biodegradable polymers. OC has been show to possess antibacterial, antitumor, immunostimulant, and wound healing properties. Currently, OC containing 16∼24% carboxyl content is commercially available in a powder or knitted fabric form for use in humans to stop bleeding during surgery and to prevent the formation and reformation of post-surgical adhesions. It has also been extensively investigated as an immobilizing matrix for a variety of drugs, enzymes, and proteins. In this study, to apply a biodegradable and biocompatible polymer, OC fibers were prepared by reaction of HNO3/H3PO4-NaNO2 with cellulose fibers which obtained from deactylation of electrospun cellulose acetate fibers. The structures of them were confirmed with FT-IR and X-ray diffractometer and the thermal properties were measured with DSC and TGA. The carboxyl content and yield of OC were measured.
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