| 초록 |
The benzopyran ring is widely found in a number of natural products such as flavonoids. These natural products have demonstrated numerous biological activities such as antiviral, antiinflammatory, antiallergic, antimutagenic and anticarcinogenic activities. In this study, a Cu-64 labeled benzopyran derivative was synthesized for investigation as a potent imaging agent for breast cancer. The reference compound was synthesized starting from 2-hydroxy-5-nitroacetophenone via six steps, and confirmed through 1H NMR spectroscopy and mass spectrometry. The radiolabeling reaction was monitored using a radio-TLC and the radiochemical and purified by HPLC. |
