화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2012년 봄 (05/09 ~ 05/11, 김대중컨벤션센터)
권호 16권 1호
발표분야 고분자
제목 Biocompatible Poly(ε-caprolactone)-block-Poly-(2-methacryloyloxyethylphosphorylcholine) copolymers synthesized by RAFT Technique
초록 Well-defined biocompatible PCL-b-PMPC diblock copolymers were synthesized by ROP and RAFT polymerization. The physio-chemical properties of the copolymers were characterized by 1H-NMR, GPC and DSC. Self-assembly of the amphiphilic copolymers was studied by TEM and DLS, which revealed that bioactive ingredient can be encapsulated by regularly spherical micelles of PCL-b-PMPC. The emulsifying ability of the copolymers was also investigated in terms of the chain length and the HLB. The PCL-b-PMPC copolymers could have important applications in the development of improved drug carriers and in the biomimetic surfactants for cosmetics.
저자 이현석, 김도훈
소속 아모레퍼시픽 기술(연)
키워드 block copolymer; PCL; MPC; ROP; RAFT
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