화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2016년 봄 (04/06 ~ 04/08, 대전컨벤션센터)
권호 41권 1호
발표분야 의료용 고분자 부문위원회 I
제목 Electric Field-responsive Conducting Polymer Nanostructures for Controlled Drug Delivery
초록 Conducting polymers have the ability to show reversible redox response for electrical stimulus-based biomedical applications. It was reported that conducting polymer-based nanoparticles (CPNs) loaded with some compounds such as drugs and growth factors showed electrically triggered drug release. Moreover, the CPNs have a huge surface-to-volume ratio, thereby providing excellent loading efficiency and highly sensitive release profiles. In this study, we prepared the drug-loaded CPNs with spherical morphology and colloidal stability by using micro-emulsion polymerization method to develop electric signal-responsive drug delivery carriers. The drug release profile was found to be finely controlled because the drug release was proportional to both number and strength of applied electric field. In conclusion, this work could open a new avenue for advance nanomedicine applications.
저자 Ahmed Ali1, 임동우2
소속 1Hanyang Univ. South Korea, 2Department of Bionanotechnology
키워드 Electric field-responsiveness; Conductive polymers; Nanostructures; Controlled drug delivery
E-Mail