| 학회 |
한국공업화학회 |
| 학술대회 |
2019년 봄 (05/01 ~ 05/03, 부산 벡스코(BEXCO)) |
| 권호 |
23권 1호 |
| 발표분야 |
생체재료_포스터 |
| 제목 |
Micro environment modified scaffolds for impanted of nephron progenitor cell for renal tissue regeneration |
| 초록 |
Renal diseases have been recognized as major health issues because of absence of efficient treatment and lack of organ donation. In our previous study, fibroblast-derived extracellular matrix was directly coated on three-dimensional porous PLGA scaffolds incorporated with magnesium hydroxide nanoparticles for renal regeneration. Herein, cell-derived ECM surface- modified scaffolds was more contained nephron progenitor cell (NPC) than only PLGA scaffolds. The viability and growth of NPC on the scaffolds also were improved. In vivo animal study demonstrated that the further developed scaffolds facilitate the paracrine effects of NPC and restore of renal functions. |
| 저자 |
김윤아1, 전소영2, 유승권3, 권태균2, 한동근4, 고원건5, 정윤기1
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| 소속 |
1한국과학기술(연), 2경북대, 3고려대, 4차의과학대, 5연세대 |
| 키워드 |
renal tissue regeneration; porous scaffold; decellularized extracellular matrix
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| E-Mail |
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