| 초록 |
Hydrogels containing benzoboroxole as a glucose-receptor have been synthesized by using a colloidal crystal as a template. After removal of a colloidal crystal template, hydrogels were obtained as a reverse-phase replica of a colloidal crystal, an inverse opal. By using acrylate monomers containing benzoboroxole, the resulting hydrogel inverse-opal could recognize monosaccharides including glucose via reversible covalent bond formation between boroxole and monosaccharide under neutral pH conditions. The swelling of hydrogels upon binding of glucose to boroxole induced a change in an optical band-gap of the hydrogel inverse opal, which could be translated into a wavelength change of reflction by the inverse opal. We demonstrated that our glucose-reponsive inverse opal could be used as a colorimetric sensor for the glucose-level in the medium at a neutral pH. |
