| 학회 | 한국화학공학회 |
| 학술대회 | 2010년 봄 (04/22 ~ 04/23, 대구 EXCO) |
| 권호 | 16권 1호, p.376 |
| 발표분야 | 생물화공 |
| 제목 | Production of gamma aminobutyric acid (GABA)from L-glutamate (MSG) by recombinant Escherichia coli strains |
| 초록 | Gamma aminobutyric acid (GABA) is the non-essential amino acid not found in natural proteins and is found in the human brain and eyes. It serves as a major inhibitory neurotransmitter with hypertensive and diuretic effects in animals. GABA has been applied in health functional foods, which may promote relaxation and relieve nervous tension. Recently, bio-based fuels and polymers have become important due to the increase of oil price and concerns about environmental pollution. Because GABA is the possible monomer for nylon 4, which is the biodegradable heat-resistant polymer, production of GABA from cheap carbon source such as L-glutamate (MSG) become important in an industrial point of view. In this presentation, we report bioconversion of L-glutamate to GABA by recombinant Escherichia coli expressing glutamate decarboxylase. Temperature, pH, and initial L-glutamate concentration during reaction were examined for the production of GABA. |
| 저자 | 박시재1, 이승환1, 김은영1, 김민정1, 최민정1, 엄경태1, 송봉근1, 이은교2 |
| 소속 | 1한국화학(연), 2한국생명공학(연) |
| 키워드 | GABA; MSG; recombinant E. coli; GAD |
| 원문파일 | 초록 보기 |
