| 학회 |
한국공업화학회 |
| 학술대회 |
2015년 가을 (11/04 ~ 11/06, 제주국제컨벤션센터(ICCJEJU)) |
| 권호 |
19권 2호 |
| 발표분야 |
생체재료_포스터 |
| 제목 |
A novel radiopaque, biodegradable polydioxanone stent for esophageal obstruction treatment |
| 초록 |
Biodegradable polydioxanone (PDO) stents were coated with hyaluronic acid-dopamine (HA-DA) and barium sulfate (BaSO4) to enhance biocompatibility, tissue adhesiveness and radio-opacity for the treatment of esophageal diseases. The HA-DA conjugate was synthesized by EDC/NHS chemistry and characterized using 1H NMR, ATR-FTIR and UV spectrometer. The amount of HA-DA on surface was quantified with micro BCA assay. The radio-opacity of BaSO4 coated PDO stents were confirmed by X-ray radiography. The tissue adhesive property was measured by ASFM F2255-05. Cyto-compatibility was evaluated with ISO 10993-5. In addition, biodegradability of the stent was measured by ISO 14855-2. Obtained results demonstrated that the PDO braided fiber coated with HA-DA and BaSO4 might be a biocompatible material as radiopaque and biodegradable polymeric stents. |
| 저자 |
정윤기1, 한동근1, 안동준2, 오민규2, 이유진1, 최슬기1
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| 소속 |
1한국과학기술(연), 2고려대 |
| 키워드 |
polydioxanone; barium sulfate; hyaluronic acid-dopamine; radiography
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| E-Mail |
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