| 학회 |
한국공업화학회 |
| 학술대회 |
2012년 봄 (05/09 ~ 05/11, 김대중컨벤션센터) |
| 권호 |
16권 1호 |
| 발표분야 |
생물공학 |
| 제목 |
Enhancement of fibroblastic proliferation from photoreactive polymer by immobilized epidermal growth factor (EGF) |
| 초록 |
The carboxymethyl starch was modified by the incorporation of an azidophenyl group to prepare photoreactive starch (Az-starch). Photo irradiation could immobilize the Az-starch on a polystylene plate and was stably retained on the surface. The immobilized Az-starch containing protein was able to immobilize by using stripe micopattern plate. The UV irradiation time and concentration of Az-starch was used to alter the physical properties of Az-starch and consequently control the release rate of the EGF. The EGF releasing Az-starch was not cytotoxic to 3T3-L1 fibroblast cells and the released epidermal growth factor maintained its activity and induced cellular proliferation in vitro. |
| 저자 |
조영민, 이형재, 손태일
|
| 소속 |
중앙대 |
| 키워드 |
Starch; azidophenyl group; epidermal growth factor (EGF); photo-immobilization; mitogenic activity
|
| E-Mail |
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