화학공학소재연구정보센터
학회 한국화학공학회
학술대회 2012년 가을 (10/24 ~ 10/26, 부산 BEXCO)
권호 18권 2호, p.1851
발표분야 생물화공
제목 Antimicrobial and biocompatible bacterial cellulose-zinc oxide nanocomposites films for biomedical applications
초록 Bacterial cellulose being widely utilized in biomedical fields especially in wound dressing and wound healing processes lacks antibacterial properties. BC nanocomposites with bactericidal elements such as zinc oxide nanoparticles (ZnONP) can overcome such limitations and improve its applications. We synthesized BC-ZnONP nanocomposite to impart antibacterial properties in the BC. Antibacterial test conducted against E. coli revealed that the BC-ZnONP strongly inhibited the bacterial growth. A visible inhibition zone was observed in BC-ZnONP samples compared to negligible effect of pure BC. The cell growth activities found through the UV absorption also indicated that the BC-ZnONP reduced the cell number in few hours and the effect remains till the observed 12 hours of incubation. On other hand cell growth quickly enhanced when incubated with the pure BC. The BC-ZnONP composites showed successful human epithelial cell attachments with very low toxicity. The BC-ZnONP composites having significant antibacterial and biocompatible properties could be safely utilized in wound dressing materials with the potential of quick and safe wound healing.
저자 Mazhar-ul-Islam, Waleed Ahmad Khattak, 강민경, 박중곤
소속 경북대
키워드 Bacterial cellulose; Zinc oxide nanoparticles; Antibacterial activities; Biocompatibility; Nanocomposites
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