화학공학소재연구정보센터
학회 한국화학공학회
학술대회 2012년 가을 (10/24 ~ 10/26, 부산 BEXCO)
권호 18권 2호, p.1712
발표분야 미립자공학
제목 Effect of variation of molar ratio on the co-crystal formation
초록 Molecular interactions responsible for the formation of molecular complexes of active pharmaceutical ingredients(APIs) with other compounds are important not only because of the ability to control pharmaceutical properties without changing covalent bonds, but also because they can be used in the design of new materials. In this study, we have found the appropriate co-former on APIs and processing conditions on co-crystal formation. we focus on the effect of molar ratio on co-crystal formation. The outcome solid forms are identified by analysis technique that powder X-ray diffration(PXRD) and differential scanning calorimetry(DSC).
저자 김다미, 김광주
소속 한밭대
키워드 crystallization; co-crystal
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