| 학회 |
한국고분자학회 |
| 학술대회 |
2009년 가을 (10/08 ~ 10/09, 광주과학기술원 오룡관) |
| 권호 |
34권 2호 |
| 발표분야 |
고분자 가공/복합재료 |
| 제목 |
Protein Encapsulation into Polymer Particles by Electrohydrodynamic Spray Drying Using Coaxial Nozzles |
| 초록 |
Spray drying is widely used for food and pharmaceutical powders, but the particle size distribution is relatively wide and not controlled easily in the tradditional process. The use of electrohydrodynamic force in spray drying offers a possibility to tailor the particle size and morphology. Electrohydrodynamic spray drying uses an electric field to induce spraying jets in addition to the air stream of spray drying. Encapsulation can be achieved by the electrohydrodynamic jetting of coaxial nozzles. The present work describes the application of novel electrohydrodynamic spray drying of coaxial nozzles for protein delivery. This simple method can microencapsulate proteins into polymer microspheres with minimal aggregation. The obtained particles were characterized by SEM, DSC and UV/Vis spectroscopy. Core/shell structure and morphology affects the release rate of the protein with respect to the thickness and channel existence in the shell. |
| 저자 |
호환기, 이종휘
|
| 소속 |
중앙대 |
| 키워드 |
Coaxial nozzles; Electrohydrodynamic spray drying; Encapsulation
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| E-Mail |
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