| 학회 |
한국고분자학회 |
| 학술대회 |
2018년 봄 (04/04 ~ 04/06, 대전컨벤션센터) |
| 권호 |
43권 1호 |
| 발표분야 |
기능성 고분자 |
| 제목 |
Dual Ionic Cross-linked Interpenetrating Network Of Alginate-cellulose Beads With Enhanced Mechanical Properties For Biocompatible Encapsulation |
| 초록 |
Spherical hydrogels made from alginate has been explored and used for biomedical application, although restricted mechanical strength and short-term structural cohesion. In this study, controlling mechanical properties and maintaining the long-term structural integrity of spherical hydrogels could be achieved by creating interpenetrating networks of alginate and aqueous-soluble cellulose with divalent and trivalent ions. We found that processing a dual sequential ionic crosslinking scheme to create IPN of alginate and cellulose with divalent and trivalent ions has synergistic effect to increase moduli and structural stability of hydrogels. As a result, the IPN alginate-cellulose beads demonstrate enhanced resistance to harsh chemical environment as compared to alginate beads and suitability for biomedical applications by encapsulating microbial species and therapeutic agents for controlled release. |
| 저자 |
이강석, 차채녕
|
| 소속 |
울산과학기술원 |
| 키워드 |
Natural Biomaterials; Commercialization; Bioreactors
|
| E-Mail |
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