| 학회 |
한국고분자학회 |
| 학술대회 |
2021년 봄 (04/07 ~ 04/09, 대전컨벤션센터) |
| 권호 |
46권 1호 |
| 발표분야 |
의료용 고분자 부문위원회 Ⅰ |
| 제목 |
Fabrication and application of lipid coated core/shell nanoparticles |
| 초록 |
Bioengineering strategies to enhance the natural targeting function of nanocarriers would magnify their therapeutic application. Here, we designed and developed the bioengineered nanocarriers to increase their retention time and achieve robust targeting by coating the surface of nanoparticles with different types of lipids. The lipid coating did not only increase the retention time of drugs and growth factors, but it also enhanced their circulation time in the body. Several types of lipids including cell membranes were tested for various applications. The reported strategy opens the door for the creation of biocompatible and custom-tailored biomimetic nanoparticles with varying hybrid functionalities, which may be used to overcome the limitations of current nanoparticle-based therapeutic and imaging platforms. |
| 저자 |
Jc Bose Rajendran1, 이수홍2, 박한수3
|
| 소속 |
1Masonic Medical Research Institute, 2동국대, 3중앙대 |
| 키워드 |
Nanoparticles; Lipid; Core Shell
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| E-Mail |
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