| 초록 |
Researchers in biomaterials have tried to solve the questions about cell activities for many decades. However, some important and clinically meaningful informations such as motility of cancer cells and neuron's activity are still not known well. Because, many obstacles are not solved yet, for example, even in vitro culturing of neuronal cell itself is challenging. Since our lab has many experience in polymer thin film coating, we have tested our previously defined as cell-adhesive and non-toxic films for neuronal cell culture. Some of the films showed the potential to be a good neuronal cell growth substrate. These films are mostly comprised of the polyelectrolytes that possess chemical functional groups which can be chemically modified by the further reaction. We used some micro-patterning and micro-structures on the coating to stimulate neuronal cells and/or cancer cells for growth and movement, which we will report in this presentation. |
