| 학회 | 한국화학공학회 |
| 학술대회 | 2010년 가을 (10/21 ~ 10/22, 대전컨벤션센터) |
| 권호 | 16권 2호, p.2034 |
| 발표분야 | 재료 |
| 제목 | Synthesis of gold-deposited fluorescent silica nanoparticles for biosensor application |
| 초록 | Gold and silica nanoparticles have been noted in bioanalysis applications recently due to high surface area, high chemical and mechanical stability and high biocompatibility. Most synthesis and deposition methods of gold nanoparticles on silica particles reported previously required extra steps to modify silica particles. Besides synthesized gold nanoparticles have wide size and shape distributions. We used a sonochemical method to provide a unique condition for the fabrication of gold nanoparticles and modification of silica nanoparticles. In this study, the fluorescent silica nanoparticles with uniform size and shape were synthesized using water-in-oil (W/O) microemulstion method and gold nanoparticles were deposited on the surface of silica under intensive ultrasound irradiation. The diameter of produced fluorescent silica nanoparticles is in the range of 58-60nm. For the application in biosensor, gold-doped red fluorescent silica nanoparticles as a biosensor was demonstrated through the attachment of gold binding polypeptide-avian influenza viral surface antigen (GBP-AIa) and the subsequent interaction with anti-avian antibody. |
| 저자 | 이경균1, 위린복2, 이석재3, 박태정2, 이재범4, 김도현2 |
| 소속 | 1한국과학기술원 생명화학공학과, 2한국과학기술원, 3나노팹, 4부산대 |
| 키워드 | 음향화학; 초음파; 실리카; 금; 바이오 |
| 원문파일 | 초록 보기 |
