학회 |
한국고분자학회 |
학술대회 |
2016년 봄 (04/06 ~ 04/08, 대전컨벤션센터) |
권호 |
41권 1호 |
발표분야 |
의료용 고분자 부문위원회 I |
제목 |
Fabrication and characterization chitosan-graft-poly (methyl vinyl ketone) nanoporous microspheres |
초록 |
Chitosan(CS) is a well-known natural polysaccharide with good biocompatibility and biodegradability. Graft copolymerization of poly (methyl vinyl ketone)[PMVK] onto chitosan was conducted by free radical method using KPS or CAN as an initiator. Nanoporous microspheres were synthesized by water-in-oil(W/O) emulsion method with glutaraldehyde(GA), Tween80® as crosslinking agent and emulsifier, followed by UV irradiation to confer nanopores by photodegradation of PMVK. Graft copolymer was characterized by FT-IR and NMR spectroscopies. SEM showed CS-g-PMVK microspheres were approximately 5 ㎛ in diameter with rough surface due to photodegradation. CS-g-PMVK could have potential applications for drug delivery system |
저자 |
이소림, 김지선, 정일두
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소속 |
부산대 |
키워드 |
nanoporous; chitosan; poly (methyl vinyl ketone); UV irradiation
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E-Mail |
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