| 학회 |
한국화학공학회 |
| 학술대회 |
2005년 봄 (04/22 ~ 04/23, 여수대학교) |
| 권호 |
11권 1호, p.1017 |
| 발표분야 |
촉매 및 반응공학 |
| 제목 |
Determination of Enantiomeric Excess in Hydrolysis and Epoxidation Reaction by Fourier Transform VCD Spectroscopy : The Comparison of Real-time Reaction Monitoring and Simulation |
| 초록 |
The first use of Fourier transform vibrational circular dichroism (FT-VCD) to follow changes in the per cent enantiomeric excess (%EE) of chiral molecules in time using a flow-cell sampling apparatus is reported. FT-VCD, as opposed to dispersive scanning VCD, eliminates the need to scan the VCD spectrum in time to monitor the % EE at more than one spectral location. The first use of partial least squares (PLS) chemometric analysis to determine %EE values from kinetic sets of VCD spectral data is also reported. These two advances have been used to monitor simultaneously changes in the fractional composition and the % EE of a mixture of two different chiral molecules which are Epichlorohydrine and Glycidol. This simulates the progress of the Hydrloysis and Epoxidation reaction from a chiral reactant to a chiral product where the %EE of both molecules can change with time. |
| 저자 |
신창교, 김상한, 김건중
|
| 소속 |
인하대 |
| 키워드 |
Vibrational Circular Dichroism; FT-VCD; Enantiomeric Excess
|
| E-Mail |
|
| 원문파일 |
초록 보기 |
