| 초록 |
Mussel-inspired adhesive molecules have been extensively used for surface functionalization of biomaterials because of their strong adhesion on various types of substrates. However, it is still challenging to enhance coating efficacy of the adhesive molecules owing to its insufficient oxidation by lack of oxygen (O2) during coating processes. Herein, we present a facile surface modification method using calcium peroxide (CP) that promote the coating efficiency of dopamine (DH) by O2 supply. We demonstrate that CP-mediated O2 supply facilitates oxidation kinetics of DH, which improves the coating efficacy of mussel-inspired biomolecules. Utilizing this system, we fabricate PEGylated surfaces to create low-binding cell culture plates, resulting in low cell attachment (5.26~9.65 % compared to control groups). In sum, our approach holds great potential as an advanced surface modification technique for a wide range of possible applications. |
