| 초록 |
As neural engineering is rapidly developed, and becoming more complex, the importance of polymeric biomaterials is getting more important. Moreover, the emerging of Optogenetics requires good optical property for those biomaterials. Therefore, biomaterials for modern, complex neural engineering need to satisfy four requirements; high transparency, biocompatibility, easy processibility, proper mechanical property. However, current polymeric biomaterials do not fulfill them. Here, we suggest a uv curable acrylate functionalized polysiloxan which shows biocompatibility, proper mechanical property, and extremely high transparency. We successfully fabricated an neural probe using the uv curable acrylate functionalized polysiloxan. The neural probe was successfully implanted to a living mouse brain with minimal tissue damage, and local field potential was successfully recorded. Taken together these results suggest that the uv curable polysiloxane acrylate might have excellent potential for being used for advanced neural engineering. |
