화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2011년 봄 (05/11 ~ 05/13, 제주국제컨벤션센터)
권호 15권 1호
발표분야 나노 정밀화학 융합 기술의 최근 동향
제목 Growth Factor-immobilized Bioactive Porous Beads for the Treatment of Urinary Incontinence
초록 Urinary incontinence is defined as the involuntary loss of urine and it is considered one of major public health concerns in aging populations. The bulking agent has usually been used as the first line therapy in the treatment of stress urinary incontinence. However, injection volume decrement over time caused by particle migration and resorption in the body has been considered as a main problem for the clinical applications. In this study, we prepared growth factor-immobilized porous polycaprolactone (PCL)/Pluronic F127 beads as an bioactive bulking agent which can provide bulking effect as well as stimulate the defect tissues around urethra for the effective treatment of urinary incontinence.
저자 오세행1, 김인걸1, 이지열2, 이진호1
소속 1한남대, 2서울성모병원
키워드 Urinary incontinence; Bulking agent; Porous beads; Growth factors
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