| 학회 |
한국화학공학회 |
| 학술대회 |
2010년 가을 (10/21 ~ 10/22, 대전컨벤션센터) |
| 권호 |
16권 2호, p.2043 |
| 발표분야 |
재료 |
| 제목 |
Highly efficient protein separation with multi-functionalizedmagneticsilicananoparticles |
| 초록 |
This work will present the development of the highly selective protein separation process with molecularly assembled silica coated magnetic nanoparticles as the cooperative functional groups. The surface modification was performed with functionalized organosilanes such as thiol-, disulfide-, and dodecyl- groups. The silica coated magnetic nanoparticles were directly produced by the sol - gel reaction of the tetraethyl orthosilicate precursor. The protein separation with cooperative functionalized magnetic nanoparticles was achieved for model protein such as bovine serum albumin (BSA) and Lysozyme (LSZ) at different pH conditions. This method has the advantages such as easy preparation, easy handling and extensive potential of biotechnology application. |
| 저자 |
안치영1, 이수연2, 이진형2, 김 웅3, 장정호2
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| 소속 |
1한국세라믹기술원 / 고려대, 2한국세라믹기술원, 3고려대 |
| 키워드 |
magnetic silica nanoparticle; surface functionalization; protein separation
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| E-Mail |
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| 원문파일 |
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