| 학회 |
한국고분자학회 |
| 학술대회 |
2017년 봄 (04/05 ~ 04/07, 대전컨벤션센터) |
| 권호 |
42권 1호 |
| 발표분야 |
고분자가공/복합재료 |
| 제목 |
Metal-enhanced fluorescence using Au@SiO2-entrapped Agarose gel microparticles for immunoassay |
| 초록 |
Metal-enhanced fluorescence (MEF) is a phenomenon that used biosensor fields because of the interaction of fluorophores with metal surface plasmon, resulting in an increased fluorescence emission. In order to intensify the signal, a constant distance between the metal surface and fluorophores. Thus to achieve that, a new structure having a uniform thickness of silica layer deposited on the gold surface was prepared. Agarose gel is easy to fabrication and has a high porosity. Therefore, we intend to carry out immunoassay by inserting the Au@SiO2 nanostructure into the agarose gel. We also fabricated agarose gel microparticles containing Au@SiO2 with various shapes using PDMS molds made by photolithography and proceeded to the suspension array to perform multiple detection. Metal-enhanced fluorescence effect by Au@SiO2 and agarose gels with various shapes enable multi-analysis systems with improved detection efficiency. |
| 저자 |
윤병주, 한상원, 민지홍, 조강희, 홍혜진, 이재상, 공혜연, 고원건
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| 소속 |
연세대 |
| 키워드 |
Metal-enhanced fluorescence; silica layer; gold surface; agarose gel; PDMS mold; photolithography
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| E-Mail |
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